Similar progression of carotid intima–media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients
Identifieur interne : 000048 ( an2020/Analysis ); précédent : 000047; suivant : 000049Similar progression of carotid intima–media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients
Auteurs : Sofia Ajeganova [Suède, Belgique] ; Thomas Gustafsson [Suède] ; Linnea Lindberg [Suède] ; Ingi Ld Hafström [Suède] ; Johan Frosteg Rd [Suède]Source :
- Lupus Science & Medicine [ 2053-8790 ] ; 2020.
Abstract
To compare progression of subclinical atherosclerosis and factors promoting it in patients with SLE and controls.
Consecutive patients with SLE and age-matched, sex-matched population controls from the SLEVIC cohort were assessed at inclusion and after 7 years with standardised data collection and carotid ultrasound. Effect of risk factors on carotid intima–media thickness (cIMT) progression was examined with adjusted linear mixed models.
A total of 77 patients and 74 controls, 68% and 61% of the original cohort, completed follow-up. The patients were (mean) 47 years old, 90% were women, and controls were 51 years old, 92% women. Patients had disease duration of (mean) 11 years, mild disease activity and low severity at both assessments. Baseline cIMT did not differ between the groups. An average absolute cIMT progression was 0.009 mm/year in patients and 0.011 mm/year in controls, intergroup difference p=0.9.
Of factors at inclusion, dyslipidaemia, lower levels of high-density lipoprotein (HDL) and carotid plaque in patients and controls, and higher systolic blood pressure, total cholesterol:HDL and LDL:HDL ratios and triglycerides in patients were associated with cIMT progression. Of factors at follow-up, hypertension and blood lipids in patients and HDL in controls were significantly associated with cIMT progression. History of lupus nephritis and a higher average dose of prednisolone used since diagnosis were associated with cIMT progression in patients. Associations of risk factors with cIMT progression were stronger in presence of plaques.
We observed a statistically comparable progression of cIMT in patients with mild SLE and controls over 7 years, which implies that progression of subclinical atherosclerosis in some patients with SLE could follow that of the general population. Traditional cardiovascular (CV) risk factors, history of lupus nephritis and higher use of corticosteroids promote cIMT progression in SLE. Detection of carotid plaque may add to CV risk stratification.
Url:
DOI: 10.1136/lupus-2019-000362
PubMed: 32095248
PubMed Central: 7008707
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000689
- to stream Pmc, to step Curation: 000689
- to stream Pmc, to step Checkpoint: 000043
- to stream Ncbi, to step Merge: 000F57
- to stream Ncbi, to step Curation: 000F57
- to stream Ncbi, to step Checkpoint: 000F57
- to stream Main, to step Merge: 000048
- to stream Main, to step Curation: 000048
- to stream Main, to step Exploration: 000048
- to stream an2020, to step Extraction: 000048
Links to Exploration step
PMC:7008707Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Similar progression of carotid intima–media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients</title><author><name sortKey="Ajeganova, Sofia" sort="Ajeganova, Sofia" uniqKey="Ajeganova S" first="Sofia" last="Ajeganova">Sofia Ajeganova</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution content-type="department">Division of Gastroenterology and Rheumatology, Department of Medicine Huddinge</institution>,<institution>Karolinska Institutet</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution content-type="department">Clinical Sciences, Rheumatology Division</institution>,<institution>Vrije Universiteit Brussel</institution>,<addr-line content-type="city">Brussels</addr-line>,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gustafsson, Thomas" sort="Gustafsson, Thomas" uniqKey="Gustafsson T" first="Thomas" last="Gustafsson">Thomas Gustafsson</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution content-type="department">Division of Clinical Physiology, Department of Laboratory Medicine and Unit of Clinical Physiology</institution>,<institution>Karolinska University Hospital</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lindberg, Linnea" sort="Lindberg, Linnea" uniqKey="Lindberg L" first="Linnea" last="Lindberg">Linnea Lindberg</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution content-type="department">Division of Clinical Physiology, Department of Laboratory Medicine and Unit of Clinical Physiology</institution>,<institution>Karolinska University Hospital</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hafstrom, Ingi Ld" sort="Hafstrom, Ingi Ld" uniqKey="Hafstrom I" first="Ingi Ld" last="Hafström">Ingi Ld Hafström</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution content-type="department">Division of Gastroenterology and Rheumatology, Department of Medicine Huddinge</institution>,<institution>Karolinska Institutet</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Frosteg Rd, Johan" sort="Frosteg Rd, Johan" uniqKey="Frosteg Rd J" first="Johan" last="Frosteg Rd">Johan Frosteg Rd</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution content-type="department">Section of Immunology and Chronic Disease, Institute of Environmental Medicine</institution>,<institution>Karolinska Institutet</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32095248</idno><idno type="pmc">7008707</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008707</idno><idno type="RBID">PMC:7008707</idno><idno type="doi">10.1136/lupus-2019-000362</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000689</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000689</idno><idno type="wicri:Area/Pmc/Curation">000689</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000689</idno><idno type="wicri:Area/Pmc/Checkpoint">000043</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000043</idno><idno type="wicri:Area/Ncbi/Merge">000F57</idno><idno type="wicri:Area/Ncbi/Curation">000F57</idno><idno type="wicri:Area/Ncbi/Checkpoint">000F57</idno><idno type="wicri:Area/Main/Merge">000048</idno><idno type="wicri:Area/Main/Curation">000048</idno><idno type="wicri:Area/Main/Exploration">000048</idno><idno type="wicri:Area/an2020/Extraction">000048</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Similar progression of carotid intima–media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients</title><author><name sortKey="Ajeganova, Sofia" sort="Ajeganova, Sofia" uniqKey="Ajeganova S" first="Sofia" last="Ajeganova">Sofia Ajeganova</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution content-type="department">Division of Gastroenterology and Rheumatology, Department of Medicine Huddinge</institution>,<institution>Karolinska Institutet</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution content-type="department">Clinical Sciences, Rheumatology Division</institution>,<institution>Vrije Universiteit Brussel</institution>,<addr-line content-type="city">Brussels</addr-line>,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gustafsson, Thomas" sort="Gustafsson, Thomas" uniqKey="Gustafsson T" first="Thomas" last="Gustafsson">Thomas Gustafsson</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution content-type="department">Division of Clinical Physiology, Department of Laboratory Medicine and Unit of Clinical Physiology</institution>,<institution>Karolinska University Hospital</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lindberg, Linnea" sort="Lindberg, Linnea" uniqKey="Lindberg L" first="Linnea" last="Lindberg">Linnea Lindberg</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution content-type="department">Division of Clinical Physiology, Department of Laboratory Medicine and Unit of Clinical Physiology</institution>,<institution>Karolinska University Hospital</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hafstrom, Ingi Ld" sort="Hafstrom, Ingi Ld" uniqKey="Hafstrom I" first="Ingi Ld" last="Hafström">Ingi Ld Hafström</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution content-type="department">Division of Gastroenterology and Rheumatology, Department of Medicine Huddinge</institution>,<institution>Karolinska Institutet</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Frosteg Rd, Johan" sort="Frosteg Rd, Johan" uniqKey="Frosteg Rd J" first="Johan" last="Frosteg Rd">Johan Frosteg Rd</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution content-type="department">Section of Immunology and Chronic Disease, Institute of Environmental Medicine</institution>,<institution>Karolinska Institutet</institution>,<addr-line content-type="city">Stockholm</addr-line>,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Lupus Science & Medicine</title><idno type="eISSN">2053-8790</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objective</title><p>To compare progression of subclinical atherosclerosis and factors promoting it in patients with SLE and controls.</p></sec><sec><title>Methods</title><p>Consecutive patients with SLE and age-matched, sex-matched population controls from the SLEVIC cohort were assessed at inclusion and after 7 years with standardised data collection and carotid ultrasound. Effect of risk factors on carotid intima–media thickness (cIMT) progression was examined with adjusted linear mixed models.</p></sec><sec><title>Results</title><p>A total of 77 patients and 74 controls, 68% and 61% of the original cohort, completed follow-up. The patients were (mean) 47 years old, 90% were women, and controls were 51 years old, 92% women. Patients had disease duration of (mean) 11 years, mild disease activity and low severity at both assessments. Baseline cIMT did not differ between the groups. An average absolute cIMT progression was 0.009 mm/year in patients and 0.011 mm/year in controls, intergroup difference p=0.9.</p><p>Of factors at inclusion, dyslipidaemia, lower levels of high-density lipoprotein (HDL) and carotid plaque in patients and controls, and higher systolic blood pressure, total cholesterol:HDL and LDL:HDL ratios and triglycerides in patients were associated with cIMT progression. Of factors at follow-up, hypertension and blood lipids in patients and HDL in controls were significantly associated with cIMT progression. History of lupus nephritis and a higher average dose of prednisolone used since diagnosis were associated with cIMT progression in patients. Associations of risk factors with cIMT progression were stronger in presence of plaques.</p></sec><sec><title>Conclusion</title><p>We observed a statistically comparable progression of cIMT in patients with mild SLE and controls over 7 years, which implies that progression of subclinical atherosclerosis in some patients with SLE could follow that of the general population. Traditional cardiovascular (CV) risk factors, history of lupus nephritis and higher use of corticosteroids promote cIMT progression in SLE. Detection of carotid plaque may add to CV risk stratification.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Tsokos, Gc" uniqKey="Tsokos G">GC Tsokos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Olesi Ska, M" uniqKey="Olesi Ska M">M Olesińska</name></author><author><name sortKey="Saletra, A" uniqKey="Saletra A">A Saletra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carter, Ee" uniqKey="Carter E">EE Carter</name></author><author><name sortKey="Barr, Sg" uniqKey="Barr S">SG Barr</name></author><author><name sortKey="Clarke, Ae" uniqKey="Clarke A">AE Clarke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frosteg Rd, J" uniqKey="Frosteg Rd J">J Frostegård</name></author><author><name sortKey="Ulfgren, A K" uniqKey="Ulfgren A">A-K Ulfgren</name></author><author><name sortKey="Nyberg, P" uniqKey="Nyberg P">P Nyberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singh, Rr" uniqKey="Singh R">RR Singh</name></author><author><name sortKey="Yen, Ey" uniqKey="Yen E">EY Yen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yen, Ey" uniqKey="Yen E">EY Yen</name></author><author><name sortKey="Shaheen, M" uniqKey="Shaheen M">M Shaheen</name></author><author><name sortKey="Jmp, W" uniqKey="Jmp W">W JMP</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schoenfeld, Sr" uniqKey="Schoenfeld S">SR Schoenfeld</name></author><author><name sortKey="Kasturi, S" uniqKey="Kasturi S">S Kasturi</name></author><author><name sortKey="Costenbader, Kh" uniqKey="Costenbader K">KH Costenbader</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giannelou, M" uniqKey="Giannelou M">M Giannelou</name></author><author><name sortKey="Nezos, A" uniqKey="Nezos A">A Nezos</name></author><author><name sortKey="Fragkioudaki, S" uniqKey="Fragkioudaki S">S Fragkioudaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clancy, R" uniqKey="Clancy R">R Clancy</name></author><author><name sortKey="El Bannoudi, H" uniqKey="El Bannoudi H">H El Bannoudi</name></author><author><name sortKey="Rasmussen, Se" uniqKey="Rasmussen S">SE Rasmussen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frosteg Rd, J" uniqKey="Frosteg Rd J">J Frostegård</name></author><author><name sortKey="Hellstrom, C" uniqKey="Hellstrom C">C Hellström</name></author><author><name sortKey="Nilsson, P" uniqKey="Nilsson P">P Nilsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kao, Ah" uniqKey="Kao A">AH Kao</name></author><author><name sortKey="Lertratanakul, A" uniqKey="Lertratanakul A">A Lertratanakul</name></author><author><name sortKey="Elliott, Jr" uniqKey="Elliott J">JR Elliott</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Di Minno, Mnd" uniqKey="Di Minno M">MND Di Minno</name></author><author><name sortKey="Emmi, G" uniqKey="Emmi G">G Emmi</name></author><author><name sortKey="Ambrosino, P" uniqKey="Ambrosino P">P Ambrosino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leonard, D" uniqKey="Leonard D">D Leonard</name></author><author><name sortKey="Svenungsson, E" uniqKey="Svenungsson E">E Svenungsson</name></author><author><name sortKey="Dahlqvist, J" uniqKey="Dahlqvist J">J Dahlqvist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anania, C" uniqKey="Anania C">C Anania</name></author><author><name sortKey="Gustafsson, T" uniqKey="Gustafsson T">T Gustafsson</name></author><author><name sortKey="Hua, X" uniqKey="Hua X">X Hua</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Henrot, P" uniqKey="Henrot P">P Henrot</name></author><author><name sortKey="Foret, J" uniqKey="Foret J">J Foret</name></author><author><name sortKey="Barnetche, T" uniqKey="Barnetche T">T Barnetche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, G C" uniqKey="Wu G">G-C Wu</name></author><author><name sortKey="Liu, H R" uniqKey="Liu H">H-R Liu</name></author><author><name sortKey="Leng, R X" uniqKey="Leng R">R-X Leng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hochberg, Mc" uniqKey="Hochberg M">MC Hochberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bombardier, C" uniqKey="Bombardier C">C Bombardier</name></author><author><name sortKey="Gladman, Dd" uniqKey="Gladman D">DD Gladman</name></author><author><name sortKey="Urowitz, Mb" uniqKey="Urowitz M">MB Urowitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gladman, D" uniqKey="Gladman D">D Gladman</name></author><author><name sortKey="Ginzler, E" uniqKey="Ginzler E">E Ginzler</name></author><author><name sortKey="Goldsmith, C" uniqKey="Goldsmith C">C Goldsmith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wendelhag, I" uniqKey="Wendelhag I">I Wendelhag</name></author><author><name sortKey="Liang, Q" uniqKey="Liang Q">Q Liang</name></author><author><name sortKey="Gustavsson, T" uniqKey="Gustavsson T">T Gustavsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fanouriakis, A" uniqKey="Fanouriakis A">A Fanouriakis</name></author><author><name sortKey="Kostopoulou, M" uniqKey="Kostopoulou M">M Kostopoulou</name></author><author><name sortKey="Alunno, A" uniqKey="Alunno A">A Alunno</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haque, S" uniqKey="Haque S">S Haque</name></author><author><name sortKey="Skeoch, S" uniqKey="Skeoch S">S Skeoch</name></author><author><name sortKey="Rakieh, C" uniqKey="Rakieh C">C Rakieh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thompson, T" uniqKey="Thompson T">T Thompson</name></author><author><name sortKey="Sutton Tyrrell, K" uniqKey="Sutton Tyrrell K">K Sutton-Tyrrell</name></author><author><name sortKey="Wildman, Rp" uniqKey="Wildman R">RP Wildman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, C Y" uniqKey="Zhang C">C-Y Zhang</name></author><author><name sortKey="Lu, L J" uniqKey="Lu L">L-J Lu</name></author><author><name sortKey="Li, F H" uniqKey="Li F">F-H Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tektonidou, Mg" uniqKey="Tektonidou M">MG Tektonidou</name></author><author><name sortKey="Kravvariti, E" uniqKey="Kravvariti E">E Kravvariti</name></author><author><name sortKey="Konstantonis, G" uniqKey="Konstantonis G">G Konstantonis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zen, M" uniqKey="Zen M">M Zen</name></author><author><name sortKey="Iaccarino, L" uniqKey="Iaccarino L">L Iaccarino</name></author><author><name sortKey="Gatto, M" uniqKey="Gatto M">M Gatto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, C" uniqKey="Sharma C">C Sharma</name></author><author><name sortKey="Raymond, W" uniqKey="Raymond W">W Raymond</name></author><author><name sortKey="Eilertsen, G" uniqKey="Eilertsen G">G Eilertsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Vollenhoven, Rf" uniqKey="Van Vollenhoven R">RF van Vollenhoven</name></author><author><name sortKey="Mosca, M" uniqKey="Mosca M">M Mosca</name></author><author><name sortKey="Bertsias, G" uniqKey="Bertsias G">G Bertsias</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Urowitz, Mb" uniqKey="Urowitz M">MB Urowitz</name></author><author><name sortKey="Su, J" uniqKey="Su J">J Su</name></author><author><name sortKey="Gladman, Dd" uniqKey="Gladman D">DD Gladman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tattersall, Mc" uniqKey="Tattersall M">MC Tattersall</name></author><author><name sortKey="Gassett, A" uniqKey="Gassett A">A Gassett</name></author><author><name sortKey="Korcarz, Ce" uniqKey="Korcarz C">CE Korcarz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Leeuw, K" uniqKey="De Leeuw K">K de Leeuw</name></author><author><name sortKey="Smit, Aj" uniqKey="Smit A">AJ Smit</name></author><author><name sortKey="De Groot, E" uniqKey="De Groot E">E de Groot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roman, Mj" uniqKey="Roman M">MJ Roman</name></author><author><name sortKey="Crow, Mk" uniqKey="Crow M">MK Crow</name></author><author><name sortKey="Lockshin, Md" uniqKey="Lockshin M">MD Lockshin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sutton Tyrrell, K" uniqKey="Sutton Tyrrell K">K Sutton-Tyrrell</name></author><author><name sortKey="Lassila, Hc" uniqKey="Lassila H">HC Lassila</name></author><author><name sortKey="Meilahn, E" uniqKey="Meilahn E">E Meilahn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fernandez Friera, L" uniqKey="Fernandez Friera L">L Fernandez-Friera</name></author><author><name sortKey="Penalvo, Jl" uniqKey="Penalvo J">JL Penalvo</name></author><author><name sortKey="Fernandez Ortiz, A" uniqKey="Fernandez Ortiz A">A Fernandez-Ortiz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tselios, K" uniqKey="Tselios K">K Tselios</name></author><author><name sortKey="Gladman, Dd" uniqKey="Gladman D">DD Gladman</name></author><author><name sortKey="Su, J" uniqKey="Su J">J Su</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Urowitz, Mb" uniqKey="Urowitz M">MB Urowitz</name></author><author><name sortKey="Gladman, Dd" uniqKey="Gladman D">DD Gladman</name></author><author><name sortKey="Anderson, Nm" uniqKey="Anderson N">NM Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thacker, Sg" uniqKey="Thacker S">SG Thacker</name></author><author><name sortKey="Zarzour, A" uniqKey="Zarzour A">A Zarzour</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhong, Q" uniqKey="Zhong Q">Q Zhong</name></author><author><name sortKey="Zhao, S" uniqKey="Zhao S">S Zhao</name></author><author><name sortKey="Yu, B" uniqKey="Yu B">B Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, N" uniqKey="Chen N">N Chen</name></author><author><name sortKey="Frishman, Wh" uniqKey="Frishman W">WH Frishman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frosteg Rd, J" uniqKey="Frosteg Rd J">J Frostegård</name></author><author><name sortKey="Svenungsson, E" uniqKey="Svenungsson E">E Svenungsson</name></author><author><name sortKey="Wu, R" uniqKey="Wu R">R Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Navab, M" uniqKey="Navab M">M Navab</name></author><author><name sortKey="Berliner, Ja" uniqKey="Berliner J">JA Berliner</name></author><author><name sortKey="Subbanagounder, G" uniqKey="Subbanagounder G">G Subbanagounder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lertratanakul, A" uniqKey="Lertratanakul A">A Lertratanakul</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P Wu</name></author><author><name sortKey="Dyer, Ar" uniqKey="Dyer A">AR Dyer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kravvariti, E" uniqKey="Kravvariti E">E Kravvariti</name></author><author><name sortKey="Konstantonis, G" uniqKey="Konstantonis G">G Konstantonis</name></author><author><name sortKey="Sfikakis, Pp" uniqKey="Sfikakis P">PP Sfikakis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gustafsson, Jt" uniqKey="Gustafsson J">JT Gustafsson</name></author><author><name sortKey="Herlitz Lindberg, M" uniqKey="Herlitz Lindberg M">M Herlitz Lindberg</name></author><author><name sortKey="Gunnarsson, I" uniqKey="Gunnarsson I">I Gunnarsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Polak, Jf" uniqKey="Polak J">JF Polak</name></author><author><name sortKey="Pencina, Mj" uniqKey="Pencina M">MJ Pencina</name></author><author><name sortKey="Pencina, Km" uniqKey="Pencina K">KM Pencina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quevedo Abeledo, Jc" uniqKey="Quevedo Abeledo J">JC Quevedo-Abeledo</name></author><author><name sortKey="Rua Figueroa, I" uniqKey="Rua Figueroa I">I Rua-Figueroa</name></author><author><name sortKey="Sanchez Perez, H" uniqKey="Sanchez Perez H">H Sanchez-Perez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tselios, K" uniqKey="Tselios K">K Tselios</name></author><author><name sortKey="Sheane, Bj" uniqKey="Sheane B">BJ Sheane</name></author><author><name sortKey="Gladman, Dd" uniqKey="Gladman D">DD Gladman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lorenz, Mw" uniqKey="Lorenz M">MW Lorenz</name></author><author><name sortKey="Markus, Hs" uniqKey="Markus H">HS Markus</name></author><author><name sortKey="Bots, Ml" uniqKey="Bots M">ML Bots</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Belgique</li><li>Suède</li></country></list><tree><country name="Suède"><noRegion><name sortKey="Ajeganova, Sofia" sort="Ajeganova, Sofia" uniqKey="Ajeganova S" first="Sofia" last="Ajeganova">Sofia Ajeganova</name></noRegion><name sortKey="Frosteg Rd, Johan" sort="Frosteg Rd, Johan" uniqKey="Frosteg Rd J" first="Johan" last="Frosteg Rd">Johan Frosteg Rd</name><name sortKey="Gustafsson, Thomas" sort="Gustafsson, Thomas" uniqKey="Gustafsson T" first="Thomas" last="Gustafsson">Thomas Gustafsson</name><name sortKey="Hafstrom, Ingi Ld" sort="Hafstrom, Ingi Ld" uniqKey="Hafstrom I" first="Ingi Ld" last="Hafström">Ingi Ld Hafström</name><name sortKey="Lindberg, Linnea" sort="Lindberg, Linnea" uniqKey="Lindberg L" first="Linnea" last="Lindberg">Linnea Lindberg</name></country><country name="Belgique"><noRegion><name sortKey="Ajeganova, Sofia" sort="Ajeganova, Sofia" uniqKey="Ajeganova S" first="Sofia" last="Ajeganova">Sofia Ajeganova</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/an2020/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000048 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/an2020/Analysis/biblio.hfd -nk 000048 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= an2020
|étape= Analysis
|type= RBID
|clé= PMC:7008707
|texte= Similar progression of carotid intima–media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/an2020/Analysis/RBID.i -Sk "pubmed:32095248" \
| HfdSelect -Kh $EXPLOR_AREA/Data/an2020/Analysis/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |